Unexpected crucial role of residue 225 in serine proteases

Residue 225 in serine proteases of the chymotrypsin family is Pro or Tyr in more than 95% of nearly 300 available sequences. Proteases with Y225 (like some blood coagulation and complement factors) are almost exclusively found in vertebrates, whereas proteases with P225 (like degradative enzymes) ar...

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Bibliografiske detaljer
Main Authors: Guinto, Enriqueta R., Caccia, Sonia, Rose, Thierry, Fütterer, Klaus, Waksman, Gabriel, Di Cera, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26700/
https://ncbi.nlm.nih.gov/pubmed/10051558
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