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Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter

The neurotoxicity of glutamate in the central nervous system is restricted by several (Na(+) + K(+))-coupled transporters for this neurotransmitter. The astroglial transporter GLT-1 is the only subtype that exhibits high sensitivity to the nontransportable glutamate analogue dihydrokainate. A marked...

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Autori principali: Zhang, Yumin, Kanner, Baruch I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC15569/
https://ncbi.nlm.nih.gov/pubmed/9990089
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