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The Stability and Transactivation Potential of the Mammalian MafA Transcription Factor Are Regulated by Serineí 65 Phosphorylation
The level of the MafA transcription factor is regulated by a variety of effectors of β cell function, including glucose, fatty acids, and insulin. Here, we show that phosphorylation at Ser(65) of mammalian MafA influences both protein stability and transactivation potential. Replacement of Ser(65) w...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613637/ https://ncbi.nlm.nih.gov/pubmed/19004825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806314200 |
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