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Phosphorylation within the MafA N Terminus Regulates C-terminal Dimerization and DNA Binding

Phosphorylation regulates transcription factor activity by influencing dimerization, cellular localization, activation potential, and/or DNA binding. Nevertheless, precisely how this post-translation modification mediates these processes is poorly understood. Here, we examined the role of phosphoryl...

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Detalhes bibliográficos
Main Authors: Guo, Shuangli, Vanderford, Nathan L., Stein, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857093/
https://ncbi.nlm.nih.gov/pubmed/20208071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105759
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