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Glucose Induces MafA Expression in Pancreatic Beta Cell Lines Via the Hexosamine Biosynthetic Pathway

MafA is a basic leucine zipper transcription factor that regulates gene expression in both the neuroretina and pancreas. Within the pancreas, MafA is exclusively expressed in the beta cells and is involved in insulin gene transcription, insulin secretion, and beta cell survival. The expression of th...

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Autors principals: Vanderford, Nathan L., Andrali, Sreenath S., Özcan, Sabire
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904346/
https://ncbi.nlm.nih.gov/pubmed/17142462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605064200
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