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Non-obese diabetic–recombination activating gene-1 (NOD–Rag 1 (null)) interleukin (IL)-2 receptor common gamma chain (IL 2 rγ(null)) null mice: a radioresistant model for human lymphohaematopoietic engraftment
Immunodeficient hosts engrafted with human lymphohaematopoietic cells hold great promise as a preclinical bridge for understanding human haematopoiesis and immunity. We now describe a new immunodeficient radioresistant non-obese diabetic mice (NOD) stock based on targeted mutations in the recombinat...
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Principais autores: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612717/ https://ncbi.nlm.nih.gov/pubmed/18785974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03753.x |
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