Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells

Immunodeficient mice bearing targeted mutations in the IL2rg gene and engrafted with human immune systems are effective tools for the study of human haematopoiesis, immunity, infectious disease and transplantation biology. The most robust human immune model is generated by implantation of human feta...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Covassin, L, Jangalwe, S, Jouvet, N, Laning, J, Burzenski, L, Shultz, L D, Brehm, M A
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2013
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826304/
https://ncbi.nlm.nih.gov/pubmed/23869841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12180
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