Improved B cell development in humanized NOD‐scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte‐macrophage colony‐stimulating factor and interleukin‐3

INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hematopoiesis and the immune response to human‐specific pathogens. A significant limitation of these humanized mouse models is, however, a severely restricted ability of human B cells to undergo class swi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Immun Inflamm Dis
Hlavní autoři: Jangalwe, Sonal, Shultz, Leonard D., Mathew, Anuja, Brehm, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134721/
https://ncbi.nlm.nih.gov/pubmed/27980777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.124
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky