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Improved B cell development in humanized NOD‐scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte‐macrophage colony‐stimulating factor and interleukin‐3
INTRODUCTION: Immunodeficient mice engrafted with human immune systems support studies of human hematopoiesis and the immune response to human‐specific pathogens. A significant limitation of these humanized mouse models is, however, a severely restricted ability of human B cells to undergo class swi...
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| Udgivet i: | Immun Inflamm Dis |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5134721/ https://ncbi.nlm.nih.gov/pubmed/27980777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.124 |
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