Artemis and Nonhomologous End Joining-Independent Influence of DNA-Dependent Protein Kinase Catalytic Subunit on Chromosome Stability

Deficiency in both ATM and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is synthetically lethal in developing mouse embryos. Using mice that phenocopy diverse aspects of Atm deficiency, we have analyzed the genetic requirements for embryonic lethality in the absence of functional DN...

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Detaylı Bibliyografya
Asıl Yazarlar: Stracker, Travis H., Williams, Bret R., Deriano, Ludovic, Theunissen, Jan W., Adelman, Carrie A., Roth, David B., Petrini, John H. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612508/
https://ncbi.nlm.nih.gov/pubmed/19015239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01354-08
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