Roles for NBS1 in alternative nonhomologous end joining of V(D)J recombination intermediates

Recent work has highlighted the importance of alternative, error-prone mechanisms for joining DNA double-strand breaks (DSB) in mammalian cells. These noncanonical, non-homologous end joining (NHEJ) pathways threaten genomic stability but remain poorly characterized. The RAG post-cleavage complex no...

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Hauptverfasser: Deriano, Ludovic, Stracker, Travis H., Baker, Annalee, Petrini, John H. J., Roth, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704125/
https://ncbi.nlm.nih.gov/pubmed/19362533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.03.009
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