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Point/Counterpoint Troponin phosphorylation and myofilament Ca(2+)-sensitivity in heart failure: increased or decreased?

Heart failure is characterised by depressed myocyte contractility and is considered to involve a complex malfunction of adrenergic regulation, Ca(2+)-handling and the contractile apparatus. Most studies on the contractile apparatus have focused on troponin, the Ca(2+)-dependent regulator of myofibri...

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Detalhes bibliográficos
Main Authors: Marston, Steven B., de Tombe, Pieter P
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610448/
https://ncbi.nlm.nih.gov/pubmed/18691597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.07.004
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