Laddar...
Uncoupling of myofilament Ca(2+)-sensitivity from troponin I phosphorylation by mutations can be reversed by Epigallocatechin-3-Gallate
AIMS: Heart muscle contraction is regulated via the β-adrenergic response that leads to phosphorylation of Troponin I (TnI) at Ser22/23, which changes the Ca(2+)-sensitivity of the cardiac myofilament. Mutations in thin filament proteins that cause Dilated Cardiomyopathy (DCM) and some mutations tha...
Sparad:
| I publikationen: | Cardiovasc Res |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905512/ https://ncbi.nlm.nih.gov/pubmed/26109583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv181 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|