Lataa...

Uncoupling of myofilament Ca(2+)-sensitivity from troponin I phosphorylation by mutations can be reversed by Epigallocatechin-3-Gallate

AIMS: Heart muscle contraction is regulated via the β-adrenergic response that leads to phosphorylation of Troponin I (TnI) at Ser22/23, which changes the Ca(2+)-sensitivity of the cardiac myofilament. Mutations in thin filament proteins that cause Dilated Cardiomyopathy (DCM) and some mutations tha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cardiovasc Res
Päätekijät: Papadaki, Maria, Vikhorev, Petr G., Marston, Steven B., Messer, Andrew E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905512/
https://ncbi.nlm.nih.gov/pubmed/26109583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv181
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!