Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts – role of myofilament Ca(2+) sensitivity increase

Troponin T (TnT) mutations that cause familial hypertrophic cardiomyopathy (FHC) and sudden cardiac death frequently increase myofilament Ca(2+) sensitivity, suggesting that their Ca(2+)-sensitizing effect contributes importantly to the FHC pathogenesis. To test this hypothesis, we compared transgen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sirenko, Syevda G, Potter, James D, Knollmann, Björn C
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819413/
https://ncbi.nlm.nih.gov/pubmed/16777946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107557
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky