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Myofilament Ca(2+) sensitization causes susceptibility to cardiac arrhythmia in mice

In human cardiomyopathy, anatomical abnormalities such as hypertrophy and fibrosis contribute to the risk of ventricular arrhythmias and sudden death. Here we have shown that increased myofilament Ca(2+) sensitivity, also a common feature in both inherited and acquired human cardiomyopathies, create...

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書誌詳細
主要な著者: Baudenbacher, Franz, Schober, Tilmann, Pinto, Jose Renato, Sidorov, Veniamin Y., Hilliard, Fredrick, Solaro, R. John, Potter, James D., Knollmann, Björn C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582931/
https://ncbi.nlm.nih.gov/pubmed/19033660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36642
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