Myofilament Ca(2+) sensitization causes susceptibility to cardiac arrhythmia in mice

In human cardiomyopathy, anatomical abnormalities such as hypertrophy and fibrosis contribute to the risk of ventricular arrhythmias and sudden death. Here we have shown that increased myofilament Ca(2+) sensitivity, also a common feature in both inherited and acquired human cardiomyopathies, create...

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Bibliografiske detaljer
Main Authors: Baudenbacher, Franz, Schober, Tilmann, Pinto, Jose Renato, Sidorov, Veniamin Y., Hilliard, Fredrick, Solaro, R. John, Potter, James D., Knollmann, Björn C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582931/
https://ncbi.nlm.nih.gov/pubmed/19033660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36642
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