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Myofilament Ca(2+) sensitization causes susceptibility to cardiac arrhythmia in mice
In human cardiomyopathy, anatomical abnormalities such as hypertrophy and fibrosis contribute to the risk of ventricular arrhythmias and sudden death. Here we have shown that increased myofilament Ca(2+) sensitivity, also a common feature in both inherited and acquired human cardiomyopathies, create...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582931/ https://ncbi.nlm.nih.gov/pubmed/19033660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36642 |
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