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Calnexin is not essential for mammalian rod opsin biogenesis

PURPOSE: Misfolding mutations in rod opsin are a major cause of the inherited blindness retinitis pigmentosa. Therefore, understanding the role of molecular chaperones in facilitating rod opsin biogenesis and the response to mutant rod opsin is important for retinal disease and fundamental retinal c...

詳細記述

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書誌詳細
主要な著者: Kosmaoglou, Maria, Cheetham, Michael E.
フォーマット: Artigo
言語:Inglês
出版事項: Molecular Vision 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610292/
https://ncbi.nlm.nih.gov/pubmed/19116670
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