Chargement en cours...
A dual role for EDEM1 in the processing of rod opsin
Mutations in rod opsin, the archetypal G-protein-coupled receptor, cause retinitis pigmentosa. The majority of mutations, e.g. P23H, cause protein misfolding, resulting in ER retention, induction of the unfolded protein response and degradation by ERAD. If misfolded rod opsin escapes degradation, it...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2009
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787460/ https://ncbi.nlm.nih.gov/pubmed/19934218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.055228 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|