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Essential Role of the Chaperonin CCT in Rod Outer Segment Biogenesis

PURPOSE. While some evidence suggests an essential role for the chaperonin containing t-complex protein 1 (CCT) in ciliogenesis, this function remains poorly understood mechanistically. We used transgenic mice, previously generated in our lab, and characterized by a genetically-induced suppression o...

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Hlavní autoři: Sinha, Satyabrata, Belcastro, Marycharmain, Datta, Poppy, Seo, Seongjin, Sokolov, Maxim
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062400/
https://ncbi.nlm.nih.gov/pubmed/24854858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13889
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