Disruption of the Chaperonin Containing TCP-1 Function Affects Protein Networks Essential for Rod Outer Segment Morphogenesis and Survival

Type II Chaperonin Containing TCP-1 (CCT, also known as TCP-1 Ring Complex, TRiC) is a multi-subunit molecular machine thought to assist in the folding of ∼10% of newly translated cytosolic proteins in eukaryotes. A number of proteins folded by CCT have been identified in yeast and cultured mammalia...

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Detalhes bibliográficos
Main Authors: Posokhova, Ekaterina, Song, Hongman, Belcastro, Marycharmain, Higgins, LeeAnn, Bigley, Lauren R., Michaud, Norman A., Martemyanov, Kirill A., Sokolov, Maxim
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013443/
https://ncbi.nlm.nih.gov/pubmed/20852191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000570
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