Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors

Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals. For instance, vertebrate rod photoreceptors use their cilia (also calle...

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Опубликовано в: :Front Mol Neurosci
Главные авторы: Brooks, Celine, Murphy, Joseph, Belcastro, Marycharmain, Heller, Daniel, Kolandaivelu, Saravanan, Kisselev, Oleg, Sokolov, Maxim
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787109/
https://ncbi.nlm.nih.gov/pubmed/29410614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00016
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