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Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1
The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II (pol II) by suppressing transient pausing of the pol II at many sites along the DNA. Elongin is composed of a transcriptionally active A subunit and two small regulatory B and C subunits, which can form an isola...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2609743/ https://ncbi.nlm.nih.gov/pubmed/19037258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.249 |
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