Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage

Elongin A performs dual functions as the transcriptionally active subunit of RNA polymerase II (Pol II) elongation factor Elongin and as the substrate recognition subunit of a Cullin-RING E3 ubiquitin ligase that ubiquitylates Pol II in response to DNA damage. Assembly of the Elongin A ubiquitin lig...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Weems, Juston C., Slaughter, Brian D., Unruh, Jay R., Boeing, Stefan, Hall, Shawn M., McLaird, Merry B., Yasukawa, Takashi, Aso, Teijiro, Svejstrup, Jesper Q., Conaway, Joan W., Conaway, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Accelerated Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399097/
https://ncbi.nlm.nih.gov/pubmed/28292928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.777946
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