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Sunlight Triggers Cutaneous Lupus through a Colony Stimulating Factor-1 (CSF-1) Dependent Mechanism in MRL-Fas(lpr) mice

Sunlight (UVB) triggers cutaneous (CLE) and systemic lupus through an unknown mechanism. We tested the hypothesis that UVB triggers CLE through a CSF-1-dependent, macrophage (Mø) -mediated mechanism in MRL-Fas(lpr) mice. By constructing mutant MRL-Fas(lpr) strains expressing varying levels of CSF-1...

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Detalhes bibliográficos
Main Authors: Menke, Julia, Hsu, Mei-Yu, Byrne, Katelyn T., Lucas, Julie A., Rabacal, Whitney A., Croker, Byron P., Zong, Xiao-Hua, Stanley, E. Richard, Kelley, Vicki R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607048/
https://ncbi.nlm.nih.gov/pubmed/18981160
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