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Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes

Vav proteins participate in the assembly of a multibranched signal transduction pathway in lymphocytes, including the stimulation of the phosphatidylinositol 3-kinase/protein kinase B and the phospholipase C-γ/Ras GDP-releasing protein/Ras/Erk routes. In the present work, we used a genetic approach...

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Hlavní autoři: Caloca, María J., Zugaza, José L., Bustelo, Xosé R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606015/
https://ncbi.nlm.nih.gov/pubmed/18974050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803814200
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