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Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3
Activation of Rho/Rac GTPases during cell signaling requires the participation of GDP/GTP exchange factors of the Dbl family. Although the structure of the catalytic core of Dbl proteins has been established recently, the molecular changes that the full-length proteins experience during normal or on...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142542/ https://ncbi.nlm.nih.gov/pubmed/15775967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600617 |
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