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Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes
Vav proteins participate in the assembly of a multibranched signal transduction pathway in lymphocytes, including the stimulation of the phosphatidylinositol 3-kinase/protein kinase B and the phospholipase C-γ/Ras GDP-releasing protein/Ras/Erk routes. In the present work, we used a genetic approach...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606015/ https://ncbi.nlm.nih.gov/pubmed/18974050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803814200 |
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