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New insights into the Vav1 activation cycle in lymphocytes

Vav1 is a hematopoietic-specific Rho GDP/GTP exchange factor and signaling adaptor. Although these activities are known to be stimulated by direct Vav1 phosphorylation, little information still exists regarding the regulatory layers that influence the overall Vav1 activation cycle. Using a collectio...

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Détails bibliographiques
Publié dans:Cell Signal
Auteurs principaux: Barreira, María, Rodríguez-Fdez, Sonia, Bustelo, Xosé R.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615736/
https://ncbi.nlm.nih.gov/pubmed/29410283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.01.026
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