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The Vav GEF Family: An Evolutionary and Functional Perspective

Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the genomes of many species has revealed that this protein family originated in choanozoans, a group of unicellular organisms from...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Rodríguez-Fdez, Sonia, Bustelo, Xosé R.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562523/
https://ncbi.nlm.nih.gov/pubmed/31100928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050465
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