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Biosynthesis of the Potent Antimalarial Compound FR900098
The antibiotics fosmidomycin and FR900098 are members of a unique class of phosphonic acid natural products that inhibit the nonmevalonate pathway for isoprenoid biosynthesis. Both are potent anti-bacterial and anti-malarial compounds, but despite their efficacy, little is known regarding their bios...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603629/ https://ncbi.nlm.nih.gov/pubmed/18721747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.07.010 |
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