ATM and Chk2 kinase target the p53 cofactor Strap

The p53 cofactor Strap (stress responsive activator of p300) is directly targeted by the DNA damage signalling pathway where phosphorylation by ATM (ataxia telangiectasia mutated) kinase facilitates nuclear accumulation. Here, we show that Strap regulation reflects the coordinated interplay between...

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Bibliografiske detaljer
Main Authors: Adams, Cassandra J, Graham, Anne L, Jansson, Martin, Coutts, Amanda S, Edelmann, Mariola, Smith, Linda, Kessler, Benedikt, La Thangue, Nicholas B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603450/
https://ncbi.nlm.nih.gov/pubmed/18833288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.186
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