The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)–fold structure

Activation of p53 target genes for tumor suppression depends on the stress-specific regulation of transcriptional coactivator complexes. Strap (stress-responsive activator of p300) is activated upon DNA damage by ataxia telangiectasia mutated (ATM) and Chk2 kinases and is a key regulator of the p53...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Adams, Cassandra J., Pike, Ashley C. W., Maniam, Sandra, Sharpe, Timothy D., Coutts, Amanda S., Knapp, Stefan, La Thangue, Nicholas B., Bullock, Alex N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309724/
https://ncbi.nlm.nih.gov/pubmed/22362889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113731109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados