The Oligonucleotide Binding (OB)-Fold Domain of KREPA4 Is Essential for Stable Incorporation into Editosomes

Most mitochondrial mRNAs in trypanosomatid parasites require uridine insertion/deletion RNA editing, a process mediated by guide RNA (gRNA) and catalyzed by multi-protein complexes called editosomes. The six oligonucleotide/oligosaccharide binding (OB)-fold proteins (KREPA1-A6), are a part of the co...

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Bibliographic Details
Main Authors: Kala, Smriti, Moshiri, Houtan, Mehta, Vaibhav, Yip, Chun Wai, Salavati, Reza
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464273/
https://ncbi.nlm.nih.gov/pubmed/23056494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046864
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