Naphthalene-based RNA Editing Inhibitor Blocks RNA Editing Activities and Editosome Assembly in Trypanosoma brucei

RNA editing, catalyzed by the multiprotein editosome complex, is an essential step for the expression of most mitochondrial genes in trypanosomatid pathogens. It has been shown previously that Trypanosoma brucei RNA editing ligase 1 (TbREL1), a core catalytic component of the editosome, is essential...

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Bibliografiset tiedot
Päätekijät: Moshiri, Houtan, Acoca, Stéphane, Kala, Smriti, Najafabadi, Hamed Shateri, Hogues, Hervé, Purisima, Enrico, Salavati, Reza
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
RNA
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077619/
https://ncbi.nlm.nih.gov/pubmed/21378165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199646
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