Naphthalene-based RNA Editing Inhibitor Blocks RNA Editing Activities and Editosome Assembly in Trypanosoma brucei

RNA editing, catalyzed by the multiprotein editosome complex, is an essential step for the expression of most mitochondrial genes in trypanosomatid pathogens. It has been shown previously that Trypanosoma brucei RNA editing ligase 1 (TbREL1), a core catalytic component of the editosome, is essential...

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Main Authors: Moshiri, Houtan, Acoca, Stéphane, Kala, Smriti, Najafabadi, Hamed Shateri, Hogues, Hervé, Purisima, Enrico, Salavati, Reza
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077619/
https://ncbi.nlm.nih.gov/pubmed/21378165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199646
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