Naphthalene-based RNA Editing Inhibitor Blocks RNA Editing Activities and Editosome Assembly in Trypanosoma brucei

RNA editing, catalyzed by the multiprotein editosome complex, is an essential step for the expression of most mitochondrial genes in trypanosomatid pathogens. It has been shown previously that Trypanosoma brucei RNA editing ligase 1 (TbREL1), a core catalytic component of the editosome, is essential...

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Bibliografske podrobnosti
Main Authors: Moshiri, Houtan, Acoca, Stéphane, Kala, Smriti, Najafabadi, Hamed Shateri, Hogues, Hervé, Purisima, Enrico, Salavati, Reza
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077619/
https://ncbi.nlm.nih.gov/pubmed/21378165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199646
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