Mutational Analysis of Trypanosoma brucei RNA Editing Ligase Reveals Regions Critical for Interaction with KREPA2

The Trypanosoma brucei parasite causes the vector-borne disease African sleeping sickness. Mitochondrial mRNAs of T. brucei undergo posttranscriptional RNA editing to make mature, functional mRNAs. The final step of this process is catalyzed by the essential ligase, T. brucei RNA Editing Ligase 1 (T...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mehta, Vaibhav, Sen, Rajashree, Moshiri, Houtan, Salavati, Reza
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366279/
https://ncbi.nlm.nih.gov/pubmed/25790471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120844
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