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Mutational Analysis of Trypanosoma brucei RNA Editing Ligase Reveals Regions Critical for Interaction with KREPA2

The Trypanosoma brucei parasite causes the vector-borne disease African sleeping sickness. Mitochondrial mRNAs of T. brucei undergo posttranscriptional RNA editing to make mature, functional mRNAs. The final step of this process is catalyzed by the essential ligase, T. brucei RNA Editing Ligase 1 (T...

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Publicat a:PLoS One
Autors principals: Mehta, Vaibhav, Sen, Rajashree, Moshiri, Houtan, Salavati, Reza
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366279/
https://ncbi.nlm.nih.gov/pubmed/25790471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120844
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