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Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase
Metabolic reprogramming is a hallmark of cancer cells. Strap (stress-responsive activator of p300) is a novel TPR motif OB-fold protein that contributes to p53 transcriptional activation. We show here that, in addition to its established transcriptional role, Strap is localised at mitochondria where...
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Foilsithe in: | Cell Death Differ |
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Main Authors: | , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Nature Publishing Group
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262780/ https://ncbi.nlm.nih.gov/pubmed/25168243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.135 |
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