ATM and Chk2 kinase target the p53 cofactor Strap

The p53 cofactor Strap (stress responsive activator of p300) is directly targeted by the DNA damage signalling pathway where phosphorylation by ATM (ataxia telangiectasia mutated) kinase facilitates nuclear accumulation. Here, we show that Strap regulation reflects the coordinated interplay between...

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Detalhes bibliográficos
Main Authors: Adams, Cassandra J, Graham, Anne L, Jansson, Martin, Coutts, Amanda S, Edelmann, Mariola, Smith, Linda, Kessler, Benedikt, La Thangue, Nicholas B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603450/
https://ncbi.nlm.nih.gov/pubmed/18833288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.186
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