The Apolar Channel in Cerebratulus lacteus Hemoglobin Is the Route for O(2) Entry and Exit

The major pathway for O(2) binding to mammalian myoglobins (Mb) and hemoglobins (Hb) involves transient upward movement of the distal histidine (His-64(E7)), allowing ligand capture in the distal pocket. The mini-globin from Cerebratulus lacteus (CerHb) appears to have an alternative pathway between...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salter, Mallory D., Nienhaus, Karin, Nienhaus, G. Ulrich, Dewilde, Sylvia, Moens, Luc, Pesce, Alessandra, Nardini, Marco, Bolognesi, Martino, Olson, John S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602902/
https://ncbi.nlm.nih.gov/pubmed/18840607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805727200
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