The Apolar Channel in Cerebratulus lacteus Hemoglobin Is the Route for O(2) Entry and Exit

The major pathway for O(2) binding to mammalian myoglobins (Mb) and hemoglobins (Hb) involves transient upward movement of the distal histidine (His-64(E7)), allowing ligand capture in the distal pocket. The mini-globin from Cerebratulus lacteus (CerHb) appears to have an alternative pathway between...

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Detalhes bibliográficos
Main Authors: Salter, Mallory D., Nienhaus, Karin, Nienhaus, G. Ulrich, Dewilde, Sylvia, Moens, Luc, Pesce, Alessandra, Nardini, Marco, Bolognesi, Martino, Olson, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602902/
https://ncbi.nlm.nih.gov/pubmed/18840607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805727200
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