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Yeast DNA Replication Protein Dpb11 Activates the Mec1/ATR Checkpoint Kinase
The Saccharomyces cerevisiae Mec1-Ddc2 protein kinase (human ATR-ATRIP) initiates a signal transduction pathway in response to DNA damage and replication stress to mediate cell cycle arrest. The yeast DNA damage checkpoint clamp Ddc1-Mec3-Rad17 (human Rad9-Hus1-Rad1: 9-1-1) is loaded around effector...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602893/ https://ncbi.nlm.nih.gov/pubmed/18922789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807435200 |
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