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Yeast DNA Replication Protein Dpb11 Activates the Mec1/ATR Checkpoint Kinase

The Saccharomyces cerevisiae Mec1-Ddc2 protein kinase (human ATR-ATRIP) initiates a signal transduction pathway in response to DNA damage and replication stress to mediate cell cycle arrest. The yeast DNA damage checkpoint clamp Ddc1-Mec3-Rad17 (human Rad9-Hus1-Rad1: 9-1-1) is loaded around effector...

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Bibliografske podrobnosti
Main Authors: Navadgi-Patil, Vasundhara M., Burgers, Peter M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602893/
https://ncbi.nlm.nih.gov/pubmed/18922789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807435200
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