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The Unstructured C-terminal Tail of Yeast Dpb11 (Human TopBP1) Protein Is Dispensable for DNA Replication and the S Phase Checkpoint but Required for the G(2)/M Checkpoint
Budding yeast Dpb11 (human TopBP1, fission yeast Cut5) is an essential protein required for replisome assembly and for the DNA damage checkpoint. Previous studies with the temperature-sensitive dpb11–1 allele, truncated at amino acid 583 of the 764-amino acid protein, have suggested the model that D...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220456/ https://ncbi.nlm.nih.gov/pubmed/21956112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.283994 |
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