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Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
Dpb11 is required for the loading of DNA polymerases α and ɛ on to DNA in chromosomal DNA replication and interacts with the DNA damage checkpoint protein Ddc1 in Saccharomyces cerevisiae. The interaction between the homologs of Dpb11 and Ddc1 in human cells and fission yeast is thought to reflect t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1513344/ https://ncbi.nlm.nih.gov/pubmed/16840526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl411 |
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