Expression, Activity, and Pro-Hypertrophic Effects of PDE5A in Cardiac Myocytes

Cyclic GMP-selective phosphodiesterase type 5 (PDE5) has been traditionally thought to play little role in cardiac myocytes, yet recent studies using selective inhibitors such as sildenafil suggest it can potently modulate acute and chronic cardiac stress responses. To date, evidence for myocyte PDE...

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Main Authors: Zhang, Manling, Koitabashi, Norimichi, Nagayama, Takahiro, Rambaran, Ryan, Feng, Ning, Takimoto, Eiki, Koenke, Trisha, O'Rourke, Brian, Champion, Hunter C., Crow, Michael T., Kass, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601628/
https://ncbi.nlm.nih.gov/pubmed/18790048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.08.012
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