Expression, Activity, and Pro-Hypertrophic Effects of PDE5A in Cardiac Myocytes

Cyclic GMP-selective phosphodiesterase type 5 (PDE5) has been traditionally thought to play little role in cardiac myocytes, yet recent studies using selective inhibitors such as sildenafil suggest it can potently modulate acute and chronic cardiac stress responses. To date, evidence for myocyte PDE...

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Detalhes bibliográficos
Main Authors: Zhang, Manling, Koitabashi, Norimichi, Nagayama, Takahiro, Rambaran, Ryan, Feng, Ning, Takimoto, Eiki, Koenke, Trisha, O'Rourke, Brian, Champion, Hunter C., Crow, Michael T., Kass, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601628/
https://ncbi.nlm.nih.gov/pubmed/18790048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.08.012
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