Llwytho...

Small- and Large-Scale Conformational Changes of Adenylate Kinase: A Molecular Dynamics Study of the Subdomain Motion and Mechanics

Adenylate kinase, an enzyme that catalyzes the phosphoryl transfer between ATP and AMP, can interconvert between the open and catalytically potent (closed) forms even without binding ligands. Several aspects of the enzyme elasticity and internal dynamics are analyzed here by atomistic molecular dyna...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pontiggia, Francesco, Zen, Andrea, Micheletti, Cristian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599863/
https://ncbi.nlm.nih.gov/pubmed/18931260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.135467
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