Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

Constitutive activation of the transcription factor STAT3 contributes to the pathogenesis of many cancers, including multiple myeloma (MM). Since STAT3 is dispensable in most normal tissue, targeted inhibition of STAT3 is an attractive therapy for patients with these cancers. To identify STAT3 inhib...

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Bibliografski detalji
Glavni autori: Nelson, Erik A., Walker, Sarah R., Kepich, Alicia, Gashin, Laurie B., Hideshima, Teru, Ikeda, Hiroshi, Chauhan, Dharminder, Anderson, Kenneth C., Frank, David A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597607/
https://ncbi.nlm.nih.gov/pubmed/18824601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-129718
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